Difference in clinical features of SARS-CoV-2 in pediatric patients before and after emergence of P.1.

ABSTRACT:

Background

The P.1 variant is a Variant of Concern announced by the WHO. The present work aimed to characterize the clinical features of pediatric patients with SARS-CoV-2 before and after the emergence of P.1.

Methods

This is a cohort study. Data of symptomatic patients younger than 18 years diagnosed with COVID-19 by PCR tests registered in Painel COVID-19 Amazonas were analyzed.

Results

A total of 4080 symptomatic pediatric patients were identified in the database between March 2020 and July 2021, of which 1654 were categorized as pre-P.1 and 978 as P.1-dominant cases, based on the prevalence of P.1 of >90% in the North Region, Brazil. Lower case-fatality rate was observed in non-infants infected during the P.1-dominant period (0.9% vs. 2.2%). In general, patients

SUBMITTER: Leung C 

PROVIDER: S-EPMC9006205 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature