Sodium-glucose cotransporter 2 inhibitors and neurological disorders: a scoping review.

ABSTRACT:

Background

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are a group of antidiabetic medications with a favourable cardiovascular, renal and overall safety profile. Given the limited treatment options available for neurological disorders, it is important to determine whether the pleiotropic effects of SGLT2i can be utilised in their prevention and management.

Methods

All articles published before 20 March 2021 were systematically searched in MEDLINE, EMBASE, Scopus, Web of Science, APA PsycINFO and ClinicalTrials.gov. Overall, 1395 titles were screened, ultimately resulting in 160 articles being included in the qualitative analysis. Screening and data extraction were conducted by two independent authors and studies were excluded if they were not an original research stu

SUBMITTER: Tharmaraja T 

PROVIDER: S-EPMC9006360 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature