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Tumor histology is an independent prognostic factor in locally advanced cervical carcinoma: A retrospective study.


ABSTRACT:

Background

Even with different histologic origins, squamous cell carcinoma (SCC) and adenocarcinoma (AC) are considered a single entity, and the first-line treatment is the same. Locally advanced disease at the diagnosis of cervical cancer is the most important prognostic factor, the recurrence rate is high, making it necessary to evaluate prognostic factors other than clinical or radiological staging; histology could be one of them but continues to be controversial. The aim of this study was to evaluate tumor histology as a prognostic factor in terms of treatment outcomes, disease-free survival (DFS) and overall survival (OS) in a retrospective cohort of patients with Locally Advanced Cervical Carcinoma (LACC).

Methods

The records of 1291patients with LACC were reviewed, al

SUBMITTER: Gallardo-Alvarado L 

PROVIDER: S-EPMC9006627 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature