The effect of body mass index on hippocampal morphology and memory performance in late childhood and adolescence.

ABSTRACT: Childhood obesity is associated with negative physiological and cognitive health outcomes. The hippocampus is a diverse subcortical structure involved in learned feeding behaviors and energy regulation, and research has shown that the hippocampus is vulnerable to the effects of excess adiposity. Previous studies have demonstrated reduced hippocampal volume in overweight and obese children; however, it is unclear if certain subregions are selectively affected. The purpose of this study was to determine how excess body weight influences regional hippocampal surface morphology and memory performance in a large cross-sectional cohort of 588 children and adolescents between 8.33 and 19.92 years of age using body mass index expressed as a percentage of the 95th percentile cutoff (%BMIp95). We de

SUBMITTER: Lynch KM 

PROVIDER: S-EPMC9006989 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature