Serum Vitamin D Status and Breast Cancer Risk by Receptor Status: A Systematic Review.

ABSTRACT:

Background

The association between vitamin D status and breast cancer risk is equivocal. No systematic reviews or meta-analyses have examined this association stratified by receptor status. Our objective is to conduct a systematic review to answer the question, "Is there a relationship between lower serum/plasma vitamin D levels and increased risk of triple negative breast cancer (TNBC) specifically?"

Methods

We systematically searched Embase and PubMed databases for published original research studies examining the risk of a breast cancer diagnosis according to vitamin D status. We excluded studies that did not provide risk estimates stratified by receptor status.

Results

Fourteen studies met our criteria, including case-control, nested case-control, and case-series

SUBMITTER: Tommie JL 

PROVIDER: S-EPMC9007063 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature