Prescribing of Gabapentinoids with or without opioids after burn injury in the US, 2012-2018.

ABSTRACT: Burn injury pain manifests as a combination of inflammatory, nociceptive, and neuropathic features. While opioids are the mainstay of burn pain management, non-opioid medications, such as gabapentinoids, have also been considered as they target the central nervous system. Increased opioid adverse events and overdose deaths in the United States led to the 2014 and 2016 guidelines to reduce opioid prescribing and consider alternatives, such as gabapentinoids. In the context of burn, the rate of gabapentinoid prescribing at the national level is unknown and it is unclear whether any shift has occurred in prescribing practices over time. We conducted a population level cohort study of adult burn patients from 2012 to 2018 to evaluate the rates and determinants of gabapentinoid prescribing, wit

SUBMITTER: Polychronopoulou E 

PROVIDER: S-EPMC9007844 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature