Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study.

ABSTRACT:

Purpose

To investigate antimicrobial use and primary and nosocomial infections in hospitalized COVID-19 patients to provide data for guidance of antimicrobial therapy.

Methods

Prospective observational cohort study conducted at Charité-Universitätsmedizin Berlin, including patients hospitalized with SARS-CoV-2-infection between March and November 2020.

Results

309 patients were included, 231 directly admitted and 78 transferred from other centres. Antimicrobial therapy was initiated in 62/231 (26.8%) of directly admitted and in 44/78 (56.4%) of transferred patients. The rate of microbiologically confirmed primary co-infections was 4.8% (11/231). Although elevated in most COVID-19 patients, C-reactive protein and procalcitonin levels were higher in patients with primar

SUBMITTER: Lingscheid T 

PROVIDER: S-EPMC9008382 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature