Preserved recognition of Omicron spike following COVID-19 messenger RNA vaccination in pregnancy.

ABSTRACT:

Background

SARS-CoV-2 infection is associated with enhanced disease severity in pregnant women. Despite the potential of COVID-19 vaccines to reduce severe disease, vaccine uptake remained relatively low among pregnant women. Just as coordinated messaging from the Centers for Disease Control and Prevention and leading obstetrics organizations began to increase vaccine confidence in this vulnerable group, the evolution of SARS-CoV-2 variants of concerns, including the Omicron variant, raised new concerns about vaccine efficacy because of their ability to escape vaccine-induced neutralizing antibodies. Early data point to a milder disease course following infection with the Omicron variant in vaccinated individuals. Thus, these data suggest that alternate vaccine-induced immunity bey

SUBMITTER: Bartsch YC 

PROVIDER: S-EPMC9008975 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature