Association Between Riboflavin Intake and Telomere Length: A Cross-Sectional Study From National Health and Nutrition Examination Survey 1999-2002.

ABSTRACT:

Background

Dietary habits and dietary intake affect telomere length, a reliable marker of biological aging and a predictor of chronic disease. Riboflavin (RF) is known as a water-soluble antioxidant vitamin, but its role in telomere length maintenance has yet to be elucidated.

Objective

The purpose of this study was to examine the relationship between dietary RF intake and telomere length in a nationally representative sample of adults.

Methods

Using the NHANES (1999-2002), telomere data of 4,298 participants aged ≥45 years were analyzed in a cross-sectional manner. Leukocyte telomere length was measured using the quantitative real-time polymerase chain reaction (qPCR). Dietary RF intake was assessed by a trained interviewer using 24-h dietary recall method. Generaliz

SUBMITTER: Chen W 

PROVIDER: S-EPMC9009291 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature