Incidence, risk factors, and prognosis of acute kidney injury in hospitalized patients with acute cholangitis.

ABSTRACT:

Background

The association between acute cholangitis (AC) and acute kidney injury (AKI) remains unclear. We investigated the incidence, and clinical course of AKI in patients with AC, and the long-term prognosis.

Methods

We performed a single-center retrospective study of patients hospitalized with AC in a tertiary care center from January 2011 to December 2017. The risk factors for AKI were evaluated, and AKI severity was analyzed using the Systemic Inflammatory Response System (SIRS), quick sequential organ failure assessment (qSOFA) score, and 2018 Tokyo Guidelines (TG) grade. To calculate the relative risk of death based on AKI, hazard ratios (HRs) and 95% confidence intervals (CIs) were obtained using Cox's proportional hazard models.

Results

A total of 1,438 pat

SUBMITTER: Lee TW 

PROVIDER: S-EPMC9009613 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature