Surveillance of Barrett's esophagus using wide-area transepithelial sampling: systematic review and meta-analysis.

ABSTRACT: Background and study aims  Wide-area transepithelial sampling (WATS) is an emerging technique that may increase dysplasia detection in Barrett's esophagus (BE). We conducted a systematic review and meta-analysis of patients who underwent surveillance for BE assessing the additional yield of WATS to forceps biopsy (FB). Methods  We searched Pubmed, Embase, Web of science, and the Cochrane library, ending in January 2021. The primary outcomes of interest were the relative and absolute increase in dysplasia detection when adding WATS to FB. Heterogeneity was assessed using I ² and Q statistic. Publication bias was assessed using funnel plots and classic fail-safe test. Results  A total of seven studies were included totaling 2,816 patients. FB ide

SUBMITTER: Qumseya B 

PROVIDER: S-EPMC9010089 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature