Chronic Kidney Disease Increases Risk of Incident HFrEF Following Percutaneous Coronary Intervention.

ABSTRACT:

Background

Chronic kidney disease (CKD) is very common in patients who are at a high risk of developing incident heart failure with reduced ejection fraction (HFrEF). However, the harmful effect of CKD on incident HFrEF has not yet been examined among patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI).

Methods

Patients undergoing PCI with baseline left ventricular ejection fraction (LVEF) ≥ 40% were included from January 2007 to December 2018 (ClinicalTrials.gov NCT04407936). We defined incident HFrEF as a follow-up LVEF of <40% within 3-12 months after discharge. Multivariable logistical regression was performed to examine the association of CKD with incident HFrEF.

Results

Overall, of 2,356 patients (mean age 62.4 ± 10.7

SUBMITTER: Lai W 

PROVIDER: S-EPMC9010558 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature