Semi-automated Segmentation and Quantification of Perivascular Spaces at 7 Tesla in COVID-19.

ABSTRACT: While COVID-19 is primarily considered a respiratory disease, it has been shown to affect the central nervous system. Mounting evidence shows that COVID-19 is associated with neurological complications as well as effects thought to be related to neuroinflammatory processes. Due to the novelty of COVID-19, there is a need to better understand the possible long-term effects it may have on patients, particularly linkage to neuroinflammatory processes. Perivascular spaces (PVS) are small fluid-filled spaces in the brain that appear on MRI scans near blood vessels and are believed to play a role in modulation of the immune response, leukocyte trafficking, and glymphatic drainage. Some studies have suggested that increased number or presence of PVS could be considered a marker of increased blood

SUBMITTER: Langan MT 

PROVIDER: S-EPMC9010775 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature