Globally Relaxed Selection and Local Adaptation in Boechera stricta.

ABSTRACT: The strength of selection varies among populations and across the genome, but the determinants of efficacy of selection remain unclear. In this study, we used whole-genome sequencing data from 467 Boechera stricta accessions to quantify the strength of selection and characterize the pattern of local adaptation. We found low genetic diversity on 0-fold degenerate sites and conserved non-coding sites, indicating functional constraints on these regions. The estimated distribution of fitness effects and the proportion of fixed substitutions suggest relaxed negative and positive selection in B. stricta. Among the four population groups, the NOR and WES groups have smaller effective population size (Ne), higher proportions of effectively neutral sites, and lower rates of adaptive evolution compa

SUBMITTER: Liang YY 

PROVIDER: S-EPMC9011030 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature