Surveillance of Safety of 3 Doses of COVID-19 mRNA Vaccination Using Electronic Health Records.

ABSTRACT:

Importance

Recent reports on waning of COVID-19 vaccine-induced immunity have led to the approval and rollout of additional doses and booster vaccinations. Individuals at increased risk of SARS-CoV-2 infection are receiving additional vaccine doses in addition to the regimen that was tested in clinical trials. Risks and adverse event profiles associated with additional vaccine doses are currently not well understood.

Objective

To evaluate the safety of third-dose vaccination with US Food and Drug Administration (FDA)-approved COVID-19 mRNA vaccines.

Design, setting, and participants

This cohort study was conducted using electronic health record (EHR) data from December 2020 to October 2021 from the multistate Mayo Clinic Enterprise. Participants included all 47 999 in

SUBMITTER: Niesen MJM 

PROVIDER: S-EPMC9011130 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature