Prognosis of Paradoxical Low-Flow Low-Gradient Aortic Stenosis: A Severe, Non-critical Form, With Surgical Treatment Benefits.

ABSTRACT:

Objectives

To determine the risk of mortality and need for aortic valve replacement (AVR) in patients with low-flow low-gradient (LFLG) aortic stenosis (AS).

Methods

A longitudinal multicentre study including consecutive patients with severe AS (aortic valve area [AVA] < 1.0 cm²) and normal left ventricular ejection fraction (LVEF). Patients were classified as: high-gradient (HG, mean gradient ≥ 40 mmHg), normal-flow low-gradient (NFLG, mean gradient < 40 mmHg, indexed systolic volume (SVi) > 35 ml/m²) and LFLG (mean gradient < 40 mmHg, SVi ≤ 35 ml/m²).

Results

Of 1,391 patients, 147 (10.5%) had LFLG, 752 (54.1%) HG, and 492 (35.4%) NFLG. Echocardiographic parameters of the LFLG group showed similar AVA to the HG group but with less se

SUBMITTER: Galian-Gay L 

PROVIDER: S-EPMC9011160 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature