Clinical and laboratory features of primary Sjogren's syndrome complicated with mild to severe thrombocytopenia.

ABSTRACT:

Background

Patients with thrombocytopenia accompanied by positive Ro/SS-A and/or La/SS-B autoantibodies have a possible diagnosis of Sjögren's syndrome (SS). Owing to its low prevalence, large-sample controlled studies on thrombocytopenia in primary SS (pSS) are scarce. Thus, this study aimed to investigate the clinical and laboratory characteristics of pSS complicated with mild to severe thrombocytopenia, and compared them with pSS patients without thrombocytopenia.

Methods

This medical records review study analyzed the demographic data, clinical manifestations, laboratory examinations, and other results of 88 patients diagnosed with pSS between March 2007 and March 2018 in the Department of Rheumatology of The First Affiliated Hospital of Soochow University. A platelet (PL

SUBMITTER: Wu J 

PROVIDER: S-EPMC9011250 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature