Polarized photoacoustic microscopy based on high-order harmonics for anisotropy detection.

ABSTRACT:

Background

Anisotropy which encodes rich structure and function information is one of the key and unique characteristics of tissues. Polarized photoacoustic imaging shows tremendous potential for the detection and quantification of the anisotropy of tissues. The existing polarized photoacoustic imaging methods cannot quantify anisotropy and detect the orientation of the optical axis in 3D imaging.

Methods

We proposed a versatile polarized photoacoustic imaging method based on the detection of high-order harmonics of the photoacoustic signal, which can be used for both 2D and 3D polarized photoacoustic imaging, This method can detect and quantify the anisotropy and the orientation of the optical axis of the anisotropic objects by the amplitude and initial phase of the high-or

SUBMITTER: Wang T 

PROVIDER: S-EPMC9011251 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature