Association of lumbar disc degeneration with low back pain in middle age in the Northern Finland Birth Cohort 1966.

ABSTRACT:

Background

Although it has been suggested that lumbar disc degeneration (LDD) is a significant risk factor for low back pain (LBP), its role remains uncertain. Our objective was to clarify the association between LDD and LBP and whether mental distress modifies the association.

Methods

Participants of a birth cohort underwent 1.5-T lumbar magnetic resonance imaging at the age of 47. The association between the sum score of LDD (Pfirrmann classification, range 0-15) and LBP (categorized into "no pain", "mild-to-moderate pain", "bothersome-and-frequent pain") was assessed using logistic regression analysis, with sex, smoking, body mass index, physical activity, occupational exposure, education, and presence of Modic changes and disc herniations as confounders. The modifying ro

SUBMITTER: Mertimo T 

PROVIDER: S-EPMC9011971 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature