Bioaccessibility of Apple Polyphenols from Peel and Flesh during Oral Digestion.

ABSTRACT: Health benefits of apple polyphenols for different chronic diseases are postulated. To exert bioactive properties, absorption into the body is required (bioavailability), which is strongly influenced by matrix release (bioaccessibility). For seven apple varieties, in vitro experiments with simulated saliva fluid (SSF) and ex vivo digestion with centrifuged human saliva were conducted. Polyphenol characterization (high-performance liquid chromatography-tandem mass spectrometry) and quantification (high performance liquid chromatography-diode array detection) was related to an aqueous methanolic extraction. A polyphenol release of 63-82% from flesh and 42-58% from peel was estimated. While hydroxycinnamic acid derivatives were released in total, a significant retention was observed for flava

SUBMITTER: Kaeswurm JAH 

PROVIDER: S-EPMC9012181 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature