Antibiotic prophylaxis for percutaneous nephrolithotomy: An updated systematic review and meta-analysis.

ABSTRACT:

Introduction

A single dose of preventive antibiotics is known to be sufficient to reduce the rate of infection-related complications in percutaneous nephrolithotomy (PCNL). However, some studies reported that the extended dose showed lower complications for high-risk groups. Therefore, we performed a systematic review and meta-analysis comparing single- and extended-dose antibiotic prophylaxis for PCNL.

Materials and methods

Relevant studies that compared single- and extended-dose antibiotic prophylactic therapies were identified. Articles were selected from PubMed, EMBASE, KoreaMed, and Google Scholar up to September 2021. Fever and systemic inflammatory response syndrome (SIRS) were compared by meta-analysis. A subgroup analysis was performed according to the degree of ris

SUBMITTER: Jung HD 

PROVIDER: S-EPMC9012355 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature