An exploratory identification of biological markers of chronic musculoskeletal pain in the low back, neck, and shoulders.

ABSTRACT:

Objectives

This study was an in-depth exploration of unique data from a nationally representative sample of adults living in the United States to identify biomarkers associated with musculoskeletal pain.

Methods

We performed secondary analyses of 2003-2004 NHANES data. After a first screening of 187 markers, analyses of 31 biomarkers were conducted on participants aged ≥20 years identified in all counties using the 2000 Census Bureau data (n = 4,742). To assess the association of each biomarker with each pain outcome (acute, subacute and chronic low back, neck, and shoulder pain), analyses were carried out using multivariable logistic regression with adjustments for sex, age and body mass index. Biomarkers were considered as continuous variables and categorized at the median

SUBMITTER: Djade CD 

PROVIDER: S-EPMC9012384 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature