Piezoelectric ultrasound energy-harvesting device for deep brain stimulation and analgesia applications.

ABSTRACT: Supplying wireless power is a challenging technical problem of great importance for implantable biomedical devices. Here, we introduce a novel implantable piezoelectric ultrasound energy-harvesting device based on Sm-doped Pb(Mg_1/3Nb_2/3)O₃-PbTiO₃ (Sm-PMN-PT) single crystal. The output power density of this device can reach up to 1.1 W/cm² in vitro, which is 18 times higher than the previous record (60 mW/cm²). After being implanted in the rat brain, under 1-MHz ultrasound with a safe intensity of 212 mW/cm², the as-developed device can produce an instantaneous effective output power of 280 μW, which can immediately activate the periaqueductal gray brain area. The rat electrophysiological experiments under anesthes

SUBMITTER: Zhang T 

PROVIDER: S-EPMC9012468 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature