Study on the Mechanism of Ustikuddus Sherbiti in Ischemic Cerebrovascular Diseases: Based on Network Pharmacology.

ABSTRACT: This paper aims to study the potential biological mechanism of Üstikuddus Sherbiti (ÜS) in the treatment of ischemic cerebrovascular diseases (ICVD) by the network pharmacology method. Traditional Chinese Medicine Systems Pharmacology (TCMSP) database was used to obtain effective constituents of ÜS by screening eligible oral utilization, drug similarity, and blood-brain barrier permeability threshold. By drug target prediction and stroke treatment target mining, 2 target data sets were analyzed to find intersection targets and the corresponding constituents were used as active constituents. An active constituent target network and an effective constituent target network were constructed by using Cytoscape 3.7.2 software. Degree parameters of the effective constituent target network were an

SUBMITTER: Gul A 

PROVIDER: S-EPMC9012636 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature