Pregnancy associated TMA in 13-year-old patient successfully treated with Eculizumab: case report.

ABSTRACT:

Background

This report introduces an unusual cause of kidney failure in a previously healthy pediatric patient. She developed thrombotic microangiopathy (TMA) that was diagnosed post-partum, requiring dialysis and eculizumab, with eventual recovery of kidney function ([chronic kidney disease (CKD) stage 3].

Case presentation

The patient was induced at term due to preeclampsia, with delivery complicated by severe postpartum hemorrhage from uterine atony. She continued to have severe hypertension post-delivery and further developed acute kidney injury (AKI) with decreased urinary output and respiratory distress requiring dialysis therapy. Labs revealed hemolysis with elevated lactate dehydrogenase, low haptoglobin, anemia, and thrombocytopenia, but otherwise unremarkable immun

SUBMITTER: Cody E 

PROVIDER: S-EPMC9013145 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature