Association of Single Nucleotide Polymorphism rs17580 with Smoking and Pulmonary Tuberculosis.

ABSTRACT: This study aimed to investigate the correlation between SERPINA1 single nucleotide polymorphism (SNP) rs17580, smoking, and pulmonary tuberculosis (TB). A total of 420 TB patients (observation group) and 640 patients without pulmonary disease (control group) were randomly included. The frequencies of different genotypes were counted in both groups, and the correlation between SNP genotypes and the occurrence of TB was analyzed. Statistical models were performed to analyze the correlation between rs17580 and TB and the correlation between rs17580. The frequencies of genotypes TT, TA, and AA at the rs17580 locus in patients with TB were not statistically different from those in the control group (P > 0.05), and the distributions of the two groups were in accordance with the Hardy-Wein

SUBMITTER: Li T 

PROVIDER: S-EPMC9013310 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature