Dynamic Alterations in Blood Flow in Glaucoma Measured with Laser Speckle Contrast Imaging.

ABSTRACT:

Purpose

To assess the repeatability of blood flow velocity index (BFVi) metrics obtained with a recently Food and Drug Administration-cleared laser speckle contrast imaging device, the XyCAM RI (Vasoptic Medical, Inc), and to characterize differences in these metrics among control, glaucoma suspect, and glaucoma participants.

Design

Prospective, observational study.

Participants

Forty-six participants: 20 control, 16 glaucoma suspect, and 10 glaucoma participants, 1 eye per participant.

Methods

Key dynamic BFVi metrics-mean, peak, dip, volumetric rise index (VRI), volumetric fall index (VFI), time to rise (TtR), time to fall (TtF), blow-out time (BOT), skew, and acceleration time index-were measured in the optic disc, optic disc vessels, optic disc perfusion re

SUBMITTER: Vinnett A 

PROVIDER: S-EPMC9013729 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature