Risk Factors of Silicosis Progression: A Retrospective Cohort Study in China.

ABSTRACT:

Background

Silicosis poses a threat to workers' health due to the irreversible lung lesions.

Design

A retrospective cohort study.

Methods

A total of 259 patients [80 worked with artificial stone (AS), 179 with non-artificial stone (non-AS)] with confirmed silicosis were included in this study. Forty-one of AS and 91 of non-AS had approximately 2 years' follow-up records [lung function tests and high-resolution computer tomography (HRCT)]. Compared with the first records, increased, densified, or newly emerging lesions in lung HRCT images were judged as progression of the disease. Cox proportional hazards models were used to determine the risk factors. Kaplan-Meier survival curve and log-rank test were used to compare prognostic factors for cumulative risk of progressi

SUBMITTER: Quan H 

PROVIDER: S-EPMC9013759 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature