Association between PCV13 pneumococcal vaccination and risk of hospital admissions due to pneumonia or sepsis among patients with haematological malignancies: a single-centre retrospective cohort study in Israel.

ABSTRACT:

Objectives

Patients with haematological malignancies receiving immunosuppressive therapy are at highest risk of invasive pneumococcal disease. Our goal was to investigate whether vaccination of haematological patients with pneumococcal 13-valent conjugated vaccine (PCV13) prior to therapy initiation is associated with decreased hospital admissions due to pneumonia or sepsis within 12 months.

Design and setting

A longitudinal retrospective cohort study was conducted at the haematology unit of Carmel Medical Center, Israel.

Participants

Information on adult patients (>18 years) who were diagnosed between 1 January 2009 and 30 December 2019 with haematological malignancies and received immunosuppressive therapy was retrieved from the electronic health records. Patients w

SUBMITTER: Draliuk R 

PROVIDER: S-EPMC9013985 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature