Beta-Blocker Dose Stratifies Mortality Risk in a Racially Diverse Heart Failure Population.

ABSTRACT: Heart failure (HF) is highly prevalent and a major cause of death in the United States. The effect of HF medications on survival has been predicted by validated models studied in populations predominantly of European descent. This study aimed to identify medications associated with survival in a racially diverse HF population. Patients with HF were recruited and followed from 2001 to 2015. Data were collected from electronic health records and the Social Security Death Index. The primary analysis tested the association between medication dose and all-cause mortality, with a secondary analysis assessing the composite outcome of death or cardiac-related hospitalization. Circulating concentration of the fibrotic marker procollagen type III N-terminal peptide (PIIINP) was also compared with me

SUBMITTER: Lteif C 

PROVIDER: S-EPMC9015092 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature