Idpr: A package for profiling and analyzing Intrinsically Disordered Proteins in R.

ABSTRACT: Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are proteins or protein-domains that do not have a single native structure, rather, they are a class of flexible peptides that can rapidly adopt multiple conformations. IDPs are quite abundant, and their dynamic characteristics provide unique advantages for various biological processes. The field of "unstructured biology" has emerged, in part, because of numerous computational studies that had identified the unique characteristics of IDPs and IDRs. The package 'idpr', short for Intrinsically Disordered Proteins in R, implements several R functions that match the established characteristics of IDPs to protein sequences of interest. This includes calculations of residue composition, charge-hydropathy relatio

SUBMITTER: McFadden WM 

PROVIDER: S-EPMC9015136 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature