Breakouts-A Radiological Sign of Poor Prognosis in Patients With Brain Metastases.

ABSTRACT:

Purpose

Brain metastases (BM) can present a displacing or infiltrating growth pattern, independent of the primary tumor type. Previous studies have shown that tumor cell infiltration at the macro-metastasis/brain parenchyma interface (MMPI) is correlated with poor outcome. Therefore, a pre-therapeutic, non-invasive detection tool for potential metastatic cell infiltration at the MMPI would be desirable to help identify patients who may benefit from a more aggressive local treatment strategy. The aim of this study was to identify specific magnetic resonance imaging (MRI) patterns at the MMPI in patients with BM and to correlate these patterns with patient outcome.

Patients and methods

In this retrospective analysis of a prospective BM registry, we categorized preoperative MR

SUBMITTER: Blazquez R 

PROVIDER: S-EPMC9015662 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature