Age and body mass index affect fit of spirometry Global Lung Function Initiative references in schoolchildren.

ABSTRACT:

Background

References from the Global Lung Function Initiative (GLI) are widely used to interpret children's spirometry results. We assessed fit for healthy schoolchildren.

Methods

LuftiBus in the School was a population-based cross-sectional study undertaken in 2013-2016 in the canton of Zurich, Switzerland. Parents and their children aged 6-17 years answered questionnaires about respiratory symptoms and lifestyle. Children underwent spirometry in a mobile lung function lab. We calculated GLI-based z-scores for forced expiratory volume in 1 s (FEV₁), forced vital capacity (FVC), FEV₁/FVC and forced expiratory flow for 25-75% of FVC (FEF_25-75) for healthy White participants. We defined appropriate fit to GLI references by mean values between

SUBMITTER: Mozun R 

PROVIDER: S-EPMC9016172 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature