Associations of cognitive performance with cardiovascular magnetic resonance phenotypes in the UK Biobank.

ABSTRACT:

Aims

Existing evidence suggests links between brain and cardiovascular health. We investigated associations between cognitive performance and cardiovascular magnetic resonance (CMR) phenotypes in the UK Biobank, considering a range of potential confounders.

Methods and results

We studied 29 763 participants with CMR and cognitive testing, specifically, fluid intelligence (FI, 13 verbal-numeric reasoning questions), and reaction time (RT, a timed pairs matching exercise); both were considered continuous variables for modelling. We included the following CMR metrics: left and right ventricular (LV and RV) volumes in end-diastole and end-systole, LV/RV ejection fractions, LV/RV stroke volumes, LV mass, and aortic distensibility. Multivariable linear regression models were used

SUBMITTER: Raisi-Estabragh Z 

PROVIDER: S-EPMC9016359 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature