Non-invasive brain stimulation combined with psychosocial intervention for depression: a systematic review and meta-analysis.

ABSTRACT:

Objectives

This review investigates the efficacy and safety of non-invasive brain stimulation (NIBS) combined with psychosocial intervention on depressive symptoms.

Materials and methods

We systematically searched five electronic databases from their inception to June 2021: PubMed, Embase, PsycINFO, Web of Science, and Medline. Randomized or non-randomized clinical trials in which NIBS plus psychosocial intervention was compared to control conditions in people with depressive symptoms were included.

Results

A total of 17 eligible studies with 660 participants were included. The meta-analysis results showed that NIBS combined with psychosocial therapy had a positive effect on moderate to severe depression ([SMD = - 0.46, 95%CI (- 0.90, - 0.02), I² = 73%, p <

SUBMITTER: He J 

PROVIDER: S-EPMC9016381 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature