Noise versus Resolution in Optical Chemical Imaging-How Reliable Are Our Measurements?

ABSTRACT: Optical chemical imaging has established itself as a valuable technique for visualizing analyte distributions in 2D, notably in medical, biological, and environmental applications. In particular for image acquisitions on small scales between few millimeter to the micrometer range, as well as in heterogeneous samples with steep analyte gradients, image resolution is essential. When individual pixels are inspected, however, image noise becomes a metric as relevant as image accuracy and precision, and denoising filters are applied to preserve relevant information. While denoising filters smooth the image noise, they can also lead to a loss of spatial resolution and thus to a loss of relevant information about analyte distributions. To investigate the trade-off between image resolution and noi

SUBMITTER: Zieger SE 

PROVIDER: S-EPMC9016884 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature