Maternal lipid profile in pregnancy and embryonic size: a population-based prospective cohort study.

ABSTRACT:

Background

Lipids are crucial for fetal growth and development. Maternal lipid concentrations are associated with fetal growth in the second and third trimester of pregnancy and with birth outcomes. However, it is unknown if this association starts early in pregnancy or arises later during fetal development. The aim of this study was to investigate the association between the maternal lipid profile in early pregnancy and embryonic size.

Methods

We included 1474 women from the Generation R Study, a population based prospective birth cohort. Both embryonic size and the maternal lipid profile were measured between 10 weeks + 1 day and 13 weeks + 6 days gestational age. The maternal lipid profile was defined as total cholesterol, triglycerides (TG), high-density lipoprotein chol

SUBMITTER: Gootjes DV 

PROVIDER: S-EPMC9016996 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature