Adiposity Measures and Morning Serum Cortisol in African Americans: Jackson Heart Study.

ABSTRACT:

Objective

Altered hormonal regulation, including cortisol, is a proposed mechanism linking adiposity to obesity-related disorders. We examined the association of anthropometric, adipokine, and body fat distribution measures of adiposity with morning serum cortisol in an African American (AA) cohort.

Methods

We investigated the cross-sectional associations of adiposity measures (BMI, waist circumference, leptin, adiponectin, leptin:adiponectin ratio, subcutaneous and visceral adipose tissue) and liver attenuation with cortisol in the Jackson Heart Study. Linear regression models were used to analyze the association between exposures and cortisol. Models were adjusted for multiple covariates.

Results

Among 4,211 participants, a 1-SD higher BMI and waist circumference we

SUBMITTER: Kluwe B 

PROVIDER: S-EPMC9017492 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature