Association of subtle alterations in thyroid function with presarcopenia in patients with type 2 diabetes mellitus.

ABSTRACT:

Aims/introduction

To investigate the association of subtle alterations in thyroid function with presarcopenia among patients with type 2 diabetes mellitus.

Materials and methods

A total of 1,865 adult patients with type 2 diabetes mellitus were enrolled in this cross-sectional study, excluding patients with overt thyroid dysfunction. Skeletal muscle mass measured by dual energy X-ray absorptiometry was used to assess presarcopenia. Logistic regression models were used to estimate the effects of thyroid hormones on presarcopenia, and subgroup analyses were carried out in different strata of age, sex and body mass index, respectively.

Results

Compared with the euthyroid group (Euthy), the subclinical hyperthyroidism group had an increased odds of presarcopenia (multivar

SUBMITTER: Li P 

PROVIDER: S-EPMC9017640 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature