Oxygen Cost of Walking in People With Multiple Sclerosis and Its Association With Fatigue: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

This systematic review and meta-analysis aimed to compare the oxygen cost of walking in individuals with multiple sclerosis (MS) and controls and to assess the relationship between oxygen cost of walking and fatigue in individuals with MS.

Methods

Four databases (CINAHL, MEDLINE, ProQuest, Web of Science) were searched up to September 2020. Studies were included if they recruited adults with MS and either compared oxygen cost of walking in those with MS and a control population or determined the relationship between oxygen cost of walking and fatigue. Meta-analysis of the standardized mean difference in oxygen cost of walking between individuals with MS and controls was performed.

Results

Nine studies were included in this review, of which 7 compared oxygen

SUBMITTER: Rooney S 

PROVIDER: S-EPMC9017655 | biostudies-literature | 2022 Mar-Apr

REPOSITORIES: biostudies-literature