Adaptive and optimized COVID-19 vaccination strategies across geographical regions and age groups.

ABSTRACT: We evaluate the efficiency of various heuristic strategies for allocating vaccines against COVID-19 and compare them to strategies found using optimal control theory. Our approach is based on a mathematical model which tracks the spread of disease among different age groups and across different geographical regions, and we introduce a method to combine age-specific contact data to geographical movement data. As a case study, we model the epidemic in the population of mainland Finland utilizing mobility data from a major telecom operator. Our approach allows to determine which geographical regions and age groups should be targeted first in order to minimize the number of deaths. In the scenarios that we test, we find that distributing vaccines demographically and in an age-descending order

SUBMITTER: Molla J 

PROVIDER: S-EPMC9017881 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature