Incidence of lab-confirmed dengue fever in a pediatric cohort in Delhi, India.

ABSTRACT:

Background

Our aim was to estimate the overall and age-specific incidence of lab-confirmed dengue fever using ELISA based assays among children 6 months to 15 years in Delhi.

Methods

We enrolled a cohort of 984 children aged 6 months to <14 years in South Delhi and followed-up weekly for fever for 24 months or till 15 completed years of child-age. Households of the enrolled children were geo-tagged. NS1, IgM and IgG assays were conducted using ELISA method to confirm dengue fever in children with ≥3 consecutive days of fever. Molecular typing was done in a subset of NS1 positive cases to identify the circulating serotypes.

Principal findings

We had a total of 1953 person-years (PY) of follow up. Overall, there were 4208 episodes of fever with peaks during June to Nove

SUBMITTER: Sinha B 

PROVIDER: S-EPMC9017938 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature