Putative functions of EpsK in teichuronic acid synthesis and phosphate starvation in Bacillus licheniformis.

ABSTRACT: Extracellular polymeric substances (EPSs) are extracellular macromolecules in bacteria, which function in cell growth and show potential for mechanism study and biosynthesis application. However, the biosynthesis mechanism of EPS is still not clear. We herein chose Bacillus licheniformis CGMCC 2876 as a target strain to investigate the EPS biosynthesis. epsK, a member of eps cluster, the predicted polysaccharide synthesis cluster, was overexpressed and showed that the overexpression of epsK led to a 26.54% decrease in the production of EPS and resulted in slenderer cell shape. Transcriptome analysis combined with protein-protein interactions analysis and protein modeling revealed that epsK was likely responsible for the synthesis of teichuronic acid, a su

SUBMITTER: Xu Y 

PROVIDER: S-EPMC9018123 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature