Dockground scoring benchmarks for protein docking.

ABSTRACT: Protein docking protocols typically involve global docking scan, followed by re-ranking of the scan predictions by more accurate scoring functions that are either computationally too expensive or algorithmically impossible to include in the global scan. Development and validation of scoring methodologies are often performed on scoring benchmark sets (docking decoys) which offer concise and nonredundant representation of the global docking scan output for a large and diverse set of protein-protein complexes. Two such protein-protein scoring benchmarks were built for the Dockground resource, which contains various datasets for the development and testing of protein docking methodologies. One set was generated based on the Dockground unbound docking benchmark 4, and the other based on protein

SUBMITTER: Kotthoff I 

PROVIDER: S-EPMC9018566 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature