Role of parental divorce and discord in the intergenerational transmission of alcohol use disorder.

ABSTRACT:

Background

Alcohol use disorder (AUD) has a strong familial component, and is associated with divorce and relationship discord. The purpose of this study was to test whether exposure to parental divorce and parental relationship discord contributes to the intergenerational transmission of AUD.

Methods

The sample included N = 9005 adult twins (43% female) from the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders. Participant AUD diagnoses were derived from structured clinical interviews based on DSM-IV alcohol dependence. Participants also reported on parental divorce and parental AUD. In addition, direct psychiatric interview data and measures of relationship discord were available for a subsample of parents of female-female twin pairs (855 mothers, 617 f

SUBMITTER: Salvatore JE 

PROVIDER: S-EPMC9018576 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature