Sex moderates effects of alcohol and cannabis co-use on alcohol and stress reactivity.

ABSTRACT:

Background

Simultaneous or concurrent use (co-use) of alcohol and cannabis is associated with greater use of both substances over time, academic difficulties, more severe substance use consequences, and adverse impacts on cognitive functioning than the use of a single substance or no substance use. This study examined potential neural mechanisms underlying co-use behaviors in comparison to single substance use. Specifically, we compared alcohol cue reactivity and stress-cue reactivity among individuals who reported frequent same-day co-use of alcohol and cannabis and individuals who reported only alcohol use.

Methods

The sample included 88 individuals (41 women) who reported only alcohol use and 24 individuals (8 women) who reported co-use of alcohol and cannabis on at least

SUBMITTER: Claus ED 

PROVIDER: S-EPMC9018602 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature