The association between hypomagnesemia and poor glycaemic control in type 1 diabetes is limited to insulin resistant individuals.

ABSTRACT: In a cohort of adults with type 1 diabetes, we examined the prevalence of hypomagnesemia and the correlation of serum magnesium levels with metabolic determinants, such as glycaemic control (as HbA_1c), inflammatory markers and circulating cytokines. Furthermore, we assessed if a surrogate for insulin resistance is essential for the possible association of serum magnesium with metabolic determinants. Individuals with type 1 diabetes, aged above 18 years, were included and clinical characteristics were obtained from questionnaires and clinical records. In venous blood samples we measured cytokines and adipose-tissue specific secretion proteins. Serum magnesium concentrations were measured and correlated with clinical data and laboratory measurements using univariate and multivaria

SUBMITTER: Oost LJ 

PROVIDER: S-EPMC9018833 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature