Bioprospecting endophytic fungi for bioactive metabolites and use of irradiation to improve their bioactivities.

ABSTRACT: The search for new bioactive compounds with innovative modes of action and chemistry are desperately needed to tackle the increased emergence of drug-resistant microbes. With this view, this paper was conducted for the isolation, identification, and biological evaluation of fungal endophytes of eleven different plant species. A total of 69 endophytic strains were isolated and tested for the presence of bioactive metabolites with antifungal, antibacterial, anticancer, and antioxidant properties in their extracts. Upon screening, two promising strains were found to have all the before-mentioned activities. These strains were Aspergillus sydowii isolated from the bark of Ricinus communis and Aspergillus flavus isolated from the twigs of Psidium guajava. Major compounds present in extracts of

SUBMITTER: El-Sayed ER 

PROVIDER: S-EPMC9018947 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature