Economic Evaluation of Screening for Polyomavirus Infection in Kidney Transplant Recipients: A Cost-Utility Analysis.

ABSTRACT: Screening for polyomavirus infection after kidney transplantation is recommended by clinical practice guidelines, but cost-effectiveness of this strategy is uncertain. The aim of this study was to estimate the incremental costs and benefits of routine screening for polyomavirus infection compared with no screening in kidney transplant recipients.

Methods

Probabilistic Markov models were constructed to compare the health and economic benefits of routine screening for polyomavirus infection using real-time polymerase chain reaction assay. A series of 1-way and probabilistic sensitivity analyses were conducted to define the most influential variables in the model.

Results

Monthly screening for 6 mo followed by 3 monthly screenings until 12 mo after transplant was dominant (lower

SUBMITTER: Wong G 

PROVIDER: S-EPMC9018998 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature