Inter-individual variation in objective measure of reactogenicity following COVID-19 vaccination via smartwatches and fitness bands.

ABSTRACT: The ability to identify who does or does not experience the intended immune response following vaccination could be of great value in not only managing the global trajectory of COVID-19 but also helping guide future vaccine development. Vaccine reactogenicity can potentially lead to detectable physiologic changes, thus we postulated that we could detect an individual's initial physiologic response to a vaccine by tracking changes relative to their pre-vaccine baseline using consumer wearable devices. We explored this possibility using a smartphone app-based research platform that enabled volunteers (39,701 individuals) to share their smartwatch data, as well as self-report, when appropriate, any symptoms, COVID-19 test results, and vaccination information. Of 7728 individuals who reported

SUBMITTER: Quer G 

PROVIDER: S-EPMC9019018 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature